Defining pathways.

Defining Pathways and Trade-offs Toward Universal Health Coverage; Comment on “Ethical Perspective: Five Unacceptable Trade-offs on the Path to Universal Health Coverage”

The World Health Organization’s (WHO’s) World Health Report 2010, “Health systems financing, the path to universal coverage,” promoted universal health coverage (UHC) as an aspirational objective for country health systems. Yet, in addition to the dimensions of services and coverage, distribution of coverage in the population, and financial risk protection highlighted by the report, the conside...

Signaling pathways involved in chronic myeloid leukemia pathogenesis: the importance of targeting Musashi2-Numb signaling to eradicate leukemia stem cells

Objective(s): Chronic myeloid leukemia (CML) is a myeloid clonal proliferation disease defining by the presence of the Philadelphia chromosome that shows the movement of BCR-ABL1. In this study, the critical role of the Musashi2-Numb axis in determining cell fate and relationship of the axis to important signaling pathways such as Hedgehog and Notch that are essential ...

Active pathway identification and classification with probabilistic ensembles.

A popular means of modeling metabolic networks is through identifying frequently observed pathways. However the definition of what constitutes an observation of a pathway and how to evaluate the importance of identified pathways remains unclear. In this paper we investigate different methods for defining an observed pathway and evaluate their performance with pathway classification models. We u...

High School Mathematics Pathways

Defining the Two Pathways For the purposes of planning for high school curriculum, Indiana Department of Education (IDOE) is setting forth two possible paths for high school mathematics: a traditional pathway and an integrated pathway. It is important to note that Indiana is not mandating either approach; however, IDOE encourages districts to carefully consider both options before making a deci...

‎f‎inding the defining hyperplanes of production possibility set with ‎variable‎ returns to scale using the linear independent ‎vectors‎‎

The Production Possibility Set (PPS) is defined as the set of all inputs and outputs of a system in which inputs can produce outputs‎. ‎In Data Envelopment Analysis (DEA)‎, ‎it is highly important to identify the defining hyperplanes and especially the strong defining hyperplanes of the empirical PPS‎. ‎Although DEA models can determine the efficiency of a Decision Making Unit (DMU)‎, ‎but they...

On the Defining Number of (2n - 2)-Vertex Colorings of Kn x Kn